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  • 시편절단기 Mecatome T260
  • 국내학술대회

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    국내학술대회 제목 게시판 내용
    제목(국문) 3D 바이오 프린팅을 이용한 생체 모방 혈관 네트워크 제작
    제목(영문) Construction of Bio-mimetic Vascular Networks by 3D Bioprinting
    저자 손정현 (S.J.H ,울산과학기술원 ) ▷공저자네트워크등록하기
    홍성준 (H.S.J ,울산과학기술원 ) ▷공저자네트워크등록하기
    강현욱 (Hyun-Wook Kang ,울산과학기술원, 생명과학부, 생명공학 ) ▷공저자네트워크등록하기
    초록
    초록(영문)

    One of the challenging issues in tissue engineering is a building of functional vascular network systems inside an artificial
    tissue. Without proper vascular networks, enough oxygen and nutrients cannot be provided to the cells in the artificial
    tissue. Therefore, the cells cannot maintain their viability and functionality during tissue growth and maturation without
    proper vascular networks. Also, the structure of vascular networks has a significant role in living tissues to improve the
    functionality of the cells. To fabricate a functional and well-organized vascular structure, researches using 3D bioprinting
    are actively studied due to its superior ability to produce complex structures with variable materials in desired patterns.
    Here, we propose the novel method for the fabrication of complex vascular networks using 3D bioprinting technology.
    Within fibrin hydrogel, vascular channels with a diameter of several hundred micrometers were produced by direct-writing
    an endothelial cells-laden bio-ink. And, a micro-scale angiogenic sprouting from the endothelial cells was self-induced by
    gradient of angiogenic factors by co-printing fibroblasts. This result demonstrated that the desired vascular structure pattern
    can be precisely constructed by our approach. The proposed bioprinting method has a great potential to construct biomimetic
    vascular networks within 3D artificial tissues

    keyword Key words : Tissue engineering, 3D bioprinting, Bio-mimetic vascular networks, Angiogenesis
    저널명 한국정밀공학회 추계학술대회 ▷관련저널보기
    VOL 17
    PAGE 111
    발표년도 2017
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    영문File
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