I. Development of Stimuli-responsive, Dynamic Polypeptide-based   Hydrogels for Tissue Engineering and Regenerative Medicine
  (Ministry of Education, Science and Technology, and National Research Foundation of Korea (NRF), #2010-0013284)
 

II. Development of Highly-sensitive Micro-fluidic Photonic-Sensors by   Using Nanoprobes for Human Sensing System

          (Ministry of Education, Science and Technology, and National Research Foundation of Korea, R11-2008-044-01002-0)

 

III. Development of Multi-functional Biohybrid Materials for Advanced  Drug Delivery

          (Hanyang University, #2010-0262)

IV. Chemical & Biological Detection Research

          (Agency for Defense Development (ADD), #2011-1410-007)

 

 

 

Functional BioNano Materials (FBNM) Laboratory focuses on developing a new class of functional bionano materials by artificial protein engineering and biomaterials engineering for biomedical applications. We have been working on basic research about structure-property-function relationship of the bionano materials as well as their biomedical applications, specifically Tissue Engineering, Regenerative Medicine, Drug and Gene Delivery System, Bioimaging, and Biosensing.

 

I. Development of Stimuli-responsive, Dynamic Polypeptide-based  Hydrogels for Tissue Engineering and Regenerative Medicine

 

II. Development of Highly-sensitive Micro-fluidic Photonic-Sensors by  Using Nanoprobes for Human Sensing System

 

III. Development of Multi-functional Biohybrid Materials for Advanced  Drug Delivery

 

IV. Chemical & Biological Detection Research

 

 

 

Functional Bionano Materials

Peptide-based biomaterials

Synthetic-polymer based biomaterials

Multi-compartmentals biohybrid materials

Tisssue engineering and regenerative medicine

Drug and gene delivery system

Bioimaging and biosensing

Research Figure-2

 

Synthetic Polymer-based Biomaterials

Design and synthesis of stimuli-responsive polypeptides and polymers

Development of 3D biomimetic scaffolds and injectable hydrogels for tissue engineering and regenerative medicine

Development of self-assembled nanostructures for drug delivery

Research Figure-3

 

Anisotropic Biohybrid Materials

Design and synthesis of anisotropic micro-, nano-structures

Development of stimuli-responsive anisotropic nanostructures for advanced drug delivery

Development of anisotropic biohybrid structures for biosensing

Research Figure-4

 

Photonics-based Bioimaging and Biosensing

Design and synthesis of surface enhanced Raman scattering (SERS)-based biohybrid nanostructures

SERE-based biosensing and bioimaging

Development of SERS substrates for chemical and biological detection in trace analysis

Sensing applications for early diagnosis of diseases, and forensic sciences

 

Tae-Hong Park, Asish Misra, Dong Woo Lim, Thomas W. Eyster, Sangyeul Hwang, Randy Carney, Francesco Stellacci and Joerg Lahann
Polymer Microparticles Anisotropically Functionalized with Rippled Gold Nanoparticles for Targeting of Human Endothelial Cell Membranes
Materials Research Socity (MRS) Spring Meeting, 2011, Vol. 0, No. 0, pp. 0~ 0

Dong Woo Lim
Polypeptide-based Materials for Tissue Engineering and Drug Delivery
The 9th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and the International Workshop, 2010, Vol. 0, No. 0, pp. 0~ 0

Ronald G. Larson, Mark Alumna Lopez, Dong Woo Lim, and Joerg Lahann
Complex Protein Patterns in Drying Droplets
Materials Research Society (MRS) Spring Meeting, 2010, Vol. 0, No. 0, pp. 0~ 0

Ghulam Jalani, Sangyeop Lee, Chan Woo Jung, Jaebum Choo and Dong Woo Lim
Highly Sensitive Biohybride Nanoprobes for Surface Enhanced Raman Scattering based Biosensing and Bioimaging
The 10th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on, 2011, Vol. 0, No. 0, pp. 0~ 0

Dong Woo Lim
Tunable Elastin-like Polypeptides for Biomedicine and Biotechnology
The 5th Global COE International Symposium on Frontiers in Biomaterials Science and Technology for R, 2010, Vol. 0, No. 0, pp. 0~ 0

Dong Woo Lim
Polypeptide-based Materials for Tissue Engineering and Drug Delivery
The 9th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and the International Workshop, 2010, Vol. 0, No. 0, pp. 0~ 0

Dong Woo Lim
Polypeptide-based Materials for Tissue Engineering and Drug Delivery
Hanyang University-Imperial College of London-Tokyo Institute of Technology (HIT) International Symp, 2010, Vol. 0, No. 0, pp. 0~ 0

Ngoc-Thanh Thi Nguyen, Soi Yun, Dong Woo Lim & E. K. Lee
Shielding effect of a PEG molecule of a mono-PEGylated peptide varies with PEG chain length
Preparative Biochemistry and Biotechnology, 2018, Vol. 0, No. 0, pp. 0~ 0

Ahmed Ali, Eun Young Hwang, Jaebum Choo, and Dong Woo Lim
PEGylated Nanographene–mediated Metallic Nanoparticle Clusters for Surface Enhanced Raman Scattering–based Biosensing
Analyst, 2018, Vol. 134, No. 0, pp. 2604~ 2615

Ahmed Ali, Eun Young Hwang, Jaebum Choo, and Dong Woo Lim
Nanoscale Graphene Oxide-Induced Metallic Nanoparticle Clustering for Surface-Enhanced Raman Scattering-based IgG Detection
Sensors and Actuators B: Chemical, 2018, Vol. 255, No. 0, pp. 183~ 192

Suji Choi, Joonki Hwang, Sangyeop Lee, Dong Woo Lim, Hoodon Joo, Jaebum Choo
Quantitative analysis of thyroid-stimulating hormone (TSH) using SERS-based lateral flow immunoassay
Sensors and Actuators B: Chemical, 2017, Vol. 240, No. 0, pp. 358~ 364